The HYDAK® Process
HYDAK is Biocoat's registered trademark for its immobilized hyaluronan coatings technology.
Application of the HYDAK Coatings is a relatively simple process using conventional coating equipment
and curing ovens. Usually coatings are applied by dip-coating. HYDAK Coatings can be used on both
inside and outside surfaces and on most commonly used polymers and metals.
HYDAK Advantages
- Exceptionally hydrophilic
- Lubricious when wet, preventing trauma and tissue abrasion
- Abrasion resistant
- Very thin, flexible coatings can be applied
- Biocompatible
- Non-thrombogenic
- Prevents adhesion of platelets, proteins, and microorganisms
HYDAK-coated surfaces exhibit a marked reduction or absence of:
- adsorbed platelets
- proteins
- bacteria
- acute thrombus formation
Process Steps
HYDAK Biocompatibility
As one might expect for a material that is ubiquitous in
the body, the biocompatibility of hyaluronan-modified
surfaces has been well-established and confirmed by in
vitro and in vivo tests including:
- cytotoxicity
- hemolysis
- acute systemic toxicity
HYDAK Properties
The HYDAK system of coatings affords great flexibility in tailoring biocompatible surfaces to the
requirements of medical device applications.
Physical properties are readily adapted to meet the design criteria of medical device applications:
- thickness
- wettability
- lubricity
- flexibility
- abrasion resistance
- storage stability
HYDAK Applications
The HYDAK system of coatings is versatile and has
applications in a wide variety of medical fields. Medical
devices on the market already employ this technology,
and new types of devices that require hydrophilic
coatings and biocompatible surfaces are constantly
arising. Possible applications include:
- Catheters
- Micro-catheters
- Guide Wires
- Balloons
- Introducers
- Sheaths
- Lead Wires
- Intraocular (IOL) Cartridges
- Endoscopes
- Vertebral Cages
- Meshes
- Blood contacting surfaces that require antithrombogenicity
- Sliding surfaces that require lubricity
