ABOUT BIOCOAT Company Biocoat, Inc., incorporated in 1991, is a privately-held corporation with administrative offices, manufacturing and R&D labs in Horsham, PA. The Biocoat technology for immobilizing hyaluronan and other biopolymers has its origins in work done by Ellington M. Beavers, Ph. D. and his co-workers at Columbia University in the early 80's. Business Practices Biocoat acquires biomaterials technologies through internal development, funding scientific and applied research at academic research facilities, joint development projects with other companies, cooperative research with academic researchers, and by acquiring the rights to intellectual property. Biocoat develops practical applications of its technologies in partnership with established medical device companies, who license the HYDAK® coating technology from Biocoat. Certifications/Qualifications Licensees of Biocoat's HYDAK coatings technology can be assured that the management system governing the development and manufacturing of our products meets the highest standards. Quality controls (QC) are conducted in strict conformance with cGMP regulations and are ISO 13485: 2003 certified. What is Hyaluronan? Hyaluronan is a polysaccharide of the glycosaminoglycans class. It is a unique biopolymer which is found in all tissues and body fluids in every mammalian species as well as in some bacteria. Interest in hyaluronan has increased greatly in recent years with major clinical applications in ophthalmology, in the treatment of degenerative joint disease, and in adhesion prevention after surgery. It has also found usage in cosmetic surgery for wrinkle reduction, sub-dermal fillers, and components for some tissue scaffolding technologies. It is unusually lubricious and hydrophilic. In the body, it lubricates the joints (synovial fluid) and separates most surfaces that slide over each other (tendons, sheaths). Medical-grade hyaluronan is produced on a commercial scale by a dozen or more companies in the U.S., Sweden, Canada, Italy, Israel, China, the Czech Republic, Japan, and others. Hyaluronan lends itself to cross-linking and immobilizing in various ways to produce hydrophilic, lubricious, and biocompatible surfaces which the body perceives as inert when implanted. Derivatizing and complexing hyaluronan with other substances makes it possible to create bioactive (e.g. anti-thrombogenic, anti-bacterial) surfaces. Reference: The Chemistry, Biology and Medical Applications of Hyaluronan and its Derivatives, ed. T. C. Laurent, Wenner-Gren International Series Vol. 72, Portland Press, London Biocoat, Inc. 211 Witmer Road, Horsham, PA 19044 Tel: 215-734-0888   Fax: 215-734-0889 Home   |   About Biocoat   |   Products   |   Services   |   News   |   Downloads   |   Contact Us   |   Site Map